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The Aztec people were certain ethnic groups of central Mexico who dominated large parts of Mesoamerica from the 14th to 16th centuries. During the early 16th century, outbreak of smallpox and typhus, diseases brought to the Americas by the Spanish, an estimated 80% of the indigenous population of the Valley of Mexico died. Most modern-day Mexicans are decedents of both indigenous Aztec and European ancestors.

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